Human papillomavirus 16 and head and neck squamous cell carcinoma
نویسندگان
چکیده
منابع مشابه
Human papillomavirus detection in head and neck squamous cell carcinoma
Squamous cell carcinomas of the head and neck (HNSCC) are a frequent diagnosis in anatomic pathology practice. Tobacco use and heavy alcohol consumption are known risk factors for HNSCC but in other cases human papillomavirus (HPV) is linked to carcinogenesis. HPV proteins E6 and E7 promote oncogenesis by blocking the action of p53 and pRB, respectively. An absence of p53 mutations in addition ...
متن کاملMulticentric human papillomavirus-associated head and neck squamous cell carcinoma.
BACKGROUND The purpose of this study was to present the clinicopathological features of a series of patients with human papillomavirus (HPV)-associated head and neck second primary tumors. METHODS Patients with HPV-associated head and neck second primary tumors from 3 centers were identified. HPV infection was evaluated using p16 by immunohistochemistry (IHC), high-risk HPV DNA by in situ hyb...
متن کاملHuman Papillomavirus-associated Head and Neck Squamous Cell Carcinoma Major
Head and neck squamous cell carcinoma (HNSCC) which includes the oral cavity, oropharynx and larynx is the sixth most common cancer worldwide with an estimated 633,000 incident cases and 335,000 deaths annually[1,2]. Human papillomavirus (HPV) is specifically associated with squamous cell carcinomas (SCC) of the oropharynx which encompasses the base of the tongue, lingual and palatine tonsils a...
متن کاملHuman papillomavirus type 16 and squamous cell carcinoma of the head and neck.
PURPOSE Human papillomavirus (HPV) has previously been reported to be associated with squamous cell carcinoma of the head and neck. Our objective was to investigate the presence and type of HPV infection in head and neck tumors and determine whether infection was associated with individual tumor characteristics, patients' pattern of tobacco and alcohol exposure, or with clinical outcome. EXPE...
متن کاملAbbreviations: HPV: Human Papillomavirus; TSCC: Tonsillar Squamous Cell Carcinoma; HNSCC: Head and Neck Squamous Cell Carcinoma
Head and neck squamous cell carcinoma (HNSCC) encompasses a multitude of cancer types, arising from the mucosal lining of the oral cavity, oropharynx, hypopharynx, larynx, sinonasal tract, and nasopharynx. Alcohol and tobacco are well-recognized pre-disposing factors for these cancers. Several Nordic countries (Denmark [1], Sweden [2][3], Finland [4]), the United States [5-8] and Australia [9],...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2007
ISSN: 0020-7136,1097-0215
DOI: 10.1002/ijc.22633